Astra: a generalizable report generation foundation model for 3D computed tomography

CT interpretation requires radiologists to review hundreds of volumetric slices per examination, making reporting time-consuming and highly expertise-dependent. Automated CT report generation offers a promising route to improving clinical efficiency, yet the field still lacks a generalizable CT report generation foundation model that supports multi-region reporting and remains robust across external real-world cohorts. Intrinsic inconsistencies in reporting style and diagnostic terminology across cohorts make naive joint training prone to noisy textual supervision, thereby limiting model generalizability. Here we present Astra, a generalizable CT report generation foundation model trained on 90,678 thoracoabdominal CT-report pairs (CTRgDB) with 353,671 abnormalities spanning eight organ systems. By harmonizing report style and further refining diagnostic consistency via reinforcement learning, Astra achieves style-consistent and diagnostically accurate report generation across diverse anatomical regions and institutions. Evaluating on CTRgDB and six external cohorts, Astra achieves state-of-the-art performance with a 44.1% average improvement in fine-grained diagnostic metrics (P<0.001). In real-world clinical workflows, Astra assistance accelerates chest report drafting by 29.6% and improves abdominal report completeness by 11.3% (P<0.001). Furthermore, Astra also demonstrates broad utility as a foundation for CT AI development, improving downstream diagnostic performance and scaling vision-language pretrain through high-quality report synthesis. Overall, Astra serves as a broadly accessible clinical assistant and a pivotal infrastructure for the next generation of AI-powered healthcare.

Towards 3D-Aware Video Diffusion Models: Render-Free Human Motion Control with Mesh Tokenization

Diffusion models have shown remarkable success in video generation. However, whether such models are truly aware of the 3D structure underlying visual observations, rather than simply reproducing plausible 2D projections, remains an open question. In this work, we investigate this question through human motion control, a task that requires precise modelling of 3D human geometry, motion, camera viewpoint, and scene context. Unlike prior methods that rely on rendered 2D motion guidance videos, we propose a render-free framework that conditions video generation directly on compressed 3D human mesh tokens. This representation preserves full 3D geometric information while enabling a unified token-based generation pipeline that processes video tokens jointly with motion tokens in a DiT-based architecture. This design requires the model to reason jointly about appearance, 3D structure, and camera viewpoint during video generation. Experimental results demonstrate strong performance on human motion control benchmarks, while reducing artifacts induced by view-dependent 2D guidance and trajectory-pose mismatches during editing. These findings suggest that video diffusion models, when equipped with mesh tokenization, can better capture complex 3D human structures and their interactions with the surrounding environment.

Lumos-Nexus: Efficient Frequency Bridging with Homogeneous Latent Space for Video Unified Models

Connector-based video unified models have demonstrated strong capability in instruction-grounded video synthesis, but integrating a large high-fidelity generator into the unified training loop is computationally prohibitive, limiting achievable visual quality. We therefore propose Lumos-Nexus, a training-efficient unified video generation framework that facilitates the development of strong reasoning-driven generation capabilities while significantly enhancing visual fidelity. Lumos-Nexus adopts a two-stage design: 1) During training, only a lightweight generator is aligned with the understanding block to learn to take in reasoning-driven semantic control. 2) During inference, we introduce Unified Progressive Frequency Bridging (UPFB) to progressively hand off generation to a high-capacity pretrained generator in the shared latent space, enabling coarse-to-fine refinement and producing high-fidelity videos without compromising reasoning quality. To fill the gap in reasoning-driven video generation benchmarks, we introduce VR-Bench, which assesses a model's capability to translate inferred intent into coherent and semantically aligned video content. Extensive experiments demonstrate that Lumos-Nexus achieves substantial gains in visual realism and temporal coherence on VBench, while exhibiting strong reasoning-based generative performance on VR-Bench. Code and models are available at https://jiazheng-xing.github.io/nexus-lumos-home/.

FourierMoE: Fourier Mixture-of-Experts Adaptation of Large Language Models

Parameter-efficient fine-tuning (PEFT) has emerged as a crucial paradigm for adapting large language models (LLMs) under constrained computational budgets. However, standard PEFT methods often struggle in multi-task fine-tuning settings, where diverse optimization objectives induce task interference and limited parameter budgets lead to representational deficiency. While recent approaches incorporate mixture-of-experts (MoE) to alleviate these issues, they predominantly operate in the spatial domain, which may introduce structural redundancy and parameter overhead. To overcome these limitations, we reformulate adaptation in the spectral domain. Our spectral analysis reveals that different tasks exhibit distinct frequency energy distributions, and that LLM layers display heterogeneous frequency sensitivities. Motivated by these insights, we propose FourierMoE, which integrates the MoE architecture with the inverse discrete Fourier transform (IDFT) for frequency-aware adaptation. Specifically, FourierMoE employs a frequency-adaptive router to dispatch tokens to experts specialized in distinct frequency bands. Each expert learns a set of conjugate-symmetric complex coefficients, preserving complete phase and amplitude information while theoretically guaranteeing lossless IDFT reconstruction into real-valued spatial weights. Extensive evaluations across 28 benchmarks, multiple model architectures, and scales demonstrate that FourierMoE consistently outperforms competitive baselines in both single-task and multi-task settings while using significantly fewer trainable parameters. These results highlight the promise of spectral-domain expert adaptation as an effective and parameter-efficient paradigm for LLM fine-tuning.

PHASOR: Anatomy- and Phase-Consistent Volumetric Diffusion for CT Virtual Contrast Enhancement

Contrast-enhanced computed tomography (CECT) is pivotal for highlighting tissue perfusion and vascularity, yet its clinical ubiquity is impeded by the invasive nature of contrast agents and radiation risks. While virtual contrast enhancement (VCE) offers an alternative to synthesizing CECT from non-contrast CT (NCCT), existing methods struggle with anatomical heterogeneity and spatial misalignment, leading to inconsistent enhancement patterns and incorrect details. This paper introduces PHASOR, a volumetric diffusion framework for high-fidelity CT VCE. By treating CT volumes as coherent sequences, we leverage a video diffusion model to enhance structural coherence and volumetric accuracy. To ensure anatomy-phase consistent synthesis, we introduce two complementary modules. First, anatomy-routed mixture-of-experts (AR-MoE) anchors distinct enhancement patterns to anatomical semantics, with organ-specific memory to capture salient details. Second, intensity-phase aware representation alignment (IP-REPA) highlights intricate contrast signals while mitigating the impact of imperfect spatial alignment. Extensive experiments across three datasets demonstrate that PHASOR significantly outperforms state-of-the-art methods in both synthesis quality and enhancement accuracy.

StateLinFormer: Stateful Training Enhancing Long-term Memory in Navigation

Effective navigation intelligence relies on long-term memory to support both immediate generalization and sustained adaptation. However, existing approaches face a dilemma: modular systems rely on explicit mapping but lack flexibility, while Transformer-based end-to-end models are constrained by fixed context windows, limiting persistent memory across extended interactions. We introduce StateLinFormer, a linear-attention navigation model trained with a stateful memory mechanism that preserves recurrent memory states across consecutive training segments instead of reinitializing them at each batch boundary. This training paradigm effectively approximates learning on infinitely long sequences, enabling the model to achieve long-horizon memory retention. Experiments across both MAZE and ProcTHOR environments demonstrate that StateLinFormer significantly outperforms its stateless linear-attention counterpart and standard Transformer baselines with fixed context windows. Notably, as interaction length increases, persistent stateful training substantially improves context-dependent adaptation, suggesting an enhancement in the model's In-Context Learning (ICL) capabilities for navigation tasks.

LumosX: Relate Any Identities with Their Attributes for Personalized Video Generation

Recent advances in diffusion models have significantly improved text-to-video generation, enabling personalized content creation with fine-grained control over both foreground and background elements. However, precise face-attribute alignment across subjects remains challenging, as existing methods lack explicit mechanisms to ensure intra-group consistency. Addressing this gap requires both explicit modeling strategies and face-attribute-aware data resources. We therefore propose LumosX, a framework that advances both data and model design. On the data side, a tailored collection pipeline orchestrates captions and visual cues from independent videos, while multimodal large language models (MLLMs) infer and assign subject-specific dependencies. These extracted relational priors impose a finer-grained structure that amplifies the expressive control of personalized video generation and enables the construction of a comprehensive benchmark. On the modeling side, Relational Self-Attention and Relational Cross-Attention intertwine position-aware embeddings with refined attention dynamics to inscribe explicit subject-attribute dependencies, enforcing disciplined intra-group cohesion and amplifying the separation between distinct subject clusters. Comprehensive evaluations on our benchmark demonstrate that LumosX achieves state-of-the-art performance in fine-grained, identity-consistent, and semantically aligned personalized multi-subject video generation. Code and models are available at https://jiazheng-xing.github.io/lumosx-home/.

Preference-Conditioned Reinforcement Learning for Space-Time Efficient Online 3D Bin Packing

Robotic bin packing is widely deployed in warehouse automation, with current systems achieving robust performance through heuristic and learning-based strategies. These systems must balance compact placement with rapid execution, where selecting alternative items or reorienting them can improve space utilization but introduce additional time. We propose a selection-based formulation that explicitly reasons over this trade-off: at each step, the robot evaluates multiple candidate actions, weighing expected packing benefit against estimated operational time. This enables time-aware strategies that selectively accept increased operational time when it yields meaningful spatial improvements. Our method, STEP (Space-Time Efficient Packing), uses a preference-conditioned, Transformer-based reinforcement learning policy, and allows generalization across candidate set sizes and integration with standard placement modules. It achieves a 44% reduction in operational time without compromising packing density. Additional material is available at https://step-packing.github.io.

TAROT: Test-driven and Capability-adaptive Curriculum Reinforcement Fine-tuning for Code Generation with Large Language Models

Large Language Models (LLMs) are changing the coding paradigm, known as vibe coding, yet synthesizing algorithmically sophisticated and robust code still remains a critical challenge. Incentivizing the deep reasoning capabilities of LLMs is essential to overcoming this hurdle. Reinforcement Fine-Tuning (RFT) has emerged as a promising strategy to address this need. However, most existing approaches overlook the heterogeneous difficulty and granularity inherent in test cases, leading to an imbalanced distribution of reward signals and consequently biased gradient updates during training. To address this, we propose Test-driven and cApability-adaptive cuRriculum reinfOrcement fine-Tuning (TAROT). TAROT systematically constructs, for each problem, a four-tier test suite (basic, intermediate, complex, edge), providing a controlled difficulty landscape for curriculum design and evaluation. Crucially, TAROT decouples curriculum progression from raw reward scores, enabling capability-conditioned evaluation and principled selection from a portfolio of curriculum policies rather than incidental test-case difficulty composition. This design fosters stable optimization and more efficient competency acquisition. Extensive experimental results reveal that the optimal curriculum for RFT in code generation is closely tied to a model's inherent capability, with less capable models achieving greater gains with an easy-to-hard progression, whereas more competent models excel under a hard-first curriculum. TAROT provides a reproducible method that adaptively tailors curriculum design to a model's capability, thereby consistently improving the functional correctness and robustness of the generated code. All code and data are released to foster reproducibility and advance community research at https://github.com/deep-diver/TAROT.

Vascular anatomy-aware self-supervised pre-training for X-ray angiogram analysis

X-ray angiography is the gold standard imaging modality for cardiovascular diseases. However, current deep learning approaches for X-ray angiogram analysis are severely constrained by the scarcity of annotated data. While large-scale self-supervised learning (SSL) has emerged as a promising solution, its potential in this domain remains largely unexplored, primarily due to the lack of effective SSL frameworks and large-scale datasets. To bridge this gap, we introduce a vascular anatomy-aware masked image modeling (VasoMIM) framework that explicitly integrates domain-specific anatomical knowledge. Specifically, VasoMIM comprises two key designs: an anatomy-guided masking strategy and an anatomical consistency loss. The former strategically masks vessel-containing patches to compel the model to learn robust vascular semantics, while the latter preserves structural consistency of vessels between original and reconstructed images, enhancing the discriminability of the learned representations. In conjunction with VasoMIM, we curate XA-170K, the largest X-ray angiogram pre-training dataset to date. We validate VasoMIM on four downstream tasks across six datasets, where it demonstrates superior transferability and achieves state-of-the-art performance compared to existing methods. These findings highlight the significant potential of VasoMIM as a foundation model for advancing a wide range of X-ray angiogram analysis tasks. VasoMIM and XA-170K will be available at https://github.com/Dxhuang-CASIA/XA-SSL.